This article summarizes the current knowledge and achievements on isobutanol production with Escherichia coli, Bacillus subtilis and Corynebacterium glutamicum regarding the metabolic engineering approaches and process conditions. Follow this link to learn more: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3242789/
Category: Enzymatic Hydrolosis
Enzymatic Hydrolosis webpage
Isobutanol Production in Engineered Saccharomyces cerevisiae by Overexpression of 2-ketoisovalerate decarboxylase and Valine Biosynthetic Enzymes.
In this study, construction of isobutanol production systems was attempted by overexpression of effective 2-keto acid decarboxylase (KDC) and combinatorial overexpression of valine biosynthetic enzymes in Saccharomyces cerevisiae D452-2. Follow this link to learn more: http://www.springerlink.com/content/517520v2r51516n1/?MUD=MP
Metabolic Engineering of Clostridium cellulolyticum for Production of Isobutanol from Cellulose
Producing biofuels directly from cellulose, known as consolidated bioprocessing, is believed to reduce costs substantially compared to a process in which cellulose degradation and fermentation to fuel are accomplished in separate steps. This research presents a metabolic engineering example for the development of a Clostridium cellulolyticum strain for isobutanol synthesis directly from cellulose. Follow this link to learn more: http://aem.asm.org/content/77/8/2727.short
Transgenic Microbe Converts Cellulose to Isobutanol Fuel
In the quest for inexpensive biofuels, U.S. scientists have created a genetically engineered microbe and used it to convert plant matter directly into isobutanol. Follow this link to learn more: http://www.ens-newswire.com/ens/mar2011/2011-03-08-091.html
Engineering the Isobutanol Biosynthetic Pathway in Escherichia coli by Comparison of Three Aldehyde Reductase/Alcohol Dehydrogenase Genes
This research compares the effect of various alcohol dehydrogenases (ADH) for the last step of the isobutanol production. Follow this link to learn more: http://www.springerlink.com/content/326485018556vu25/